J2357 is the HCPCS code for: Injection, omalizumab, 5 mg. In 2024, 617 providers billed J2357 3,851,801 times, with an estimated $113.4M paid by Medicare.
J2357 is a Part B drug code: Medicare pays an ASP-based rate of $46.59 per 5 mg (2026 Q3 ASP drug pricing file). Total payment per patient depends on the dose billed.
A billed "service" on this code is one 5 mg unit, not one patient visit — that's why the service counts below run high.
What Medicare actually paid per service in 2024, on average: $29.45 (observed payment across all settings and modifiers — not a fee-schedule rate).
The top 5 billers nationally, ranked by 2024 Medicare service volume.
| # | Provider | Specialty | Location | Services | Est. Medicare paid |
|---|---|---|---|---|---|
| 1 | Angela Ahuja, MD | Allergy/ Immunology | Chelmsford, MA | 44,910 | $1.3M |
| 2 | Asif Rafi, M.D. | Allergy/ Immunology | Los Angeles, CA | 43,410 | $1.3M |
| 3 | Robert Brennan, MD | Infectious Disease | Lynchburg, VA | 43,350 | $1.3M |
| 4 | Matthew Mardiney, M.D. | Allergy/ Immunology | Bel Air, MD | 37,727 | $1.1M |
| 5 | David Amran, M.D. | Allergy/ Immunology | Sugar Land, TX | 36,165 | $1.1M |
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