J2781 is the HCPCS code for: Injection, pegcetacoplan, intravitreal, 1 mg. In 2024, 857 providers billed J2781 2,452,956 times, with an estimated $286.1M paid by Medicare.
J2781 is a Part B drug code: Medicare pays an ASP-based rate of $148.94 per 1 mg (2026 Q3 ASP drug pricing file). Total payment per patient depends on the dose billed.
A billed "service" on this code is one 1 mg unit, not one patient visit — that's why the service counts below run high.
What Medicare actually paid per service in 2024, on average: $116.63 (observed payment across all settings and modifiers — not a fee-schedule rate).
The top 5 billers nationally, ranked by 2024 Medicare service volume.
| # | Provider | Specialty | Location | Services | Est. Medicare paid |
|---|---|---|---|---|---|
| 1 | David Warrow, M.D. | Ophthalmology | Hagerstown, MD | 66,975 | $7.8M |
| 2 | Allen Hu, MD | Ophthalmology | Hagerstown, MD | 52,937 | $6.2M |
| 3 | Sunil Gupta, M.D. | Ophthalmology | Pensacola, FL | 31,125 | $3.6M |
| 4 | Eric Jablon, M.D. | Ophthalmology | Charleston, SC | 23,150 | $2.7M |
| 5 | David Kim, M.D. | Ophthalmology | Glendale, CA | 18,255 | $2.1M |
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