J9271 is the HCPCS code for: Injection, pembrolizumab, 1 mg. In 2024, 1,922 providers billed J9271 28,218,856 times, with an estimated $1.2B paid by Medicare.
J9271 is a Part B drug code: Medicare pays an ASP-based rate of $60.65 per 1 mg (2026 Q3 ASP drug pricing file). Total payment per patient depends on the dose billed.
A billed "service" on this code is one 1 mg unit, not one patient visit — that's why the service counts below run high.
What Medicare actually paid per service in 2024, on average: $44.03 (observed payment across all settings and modifiers — not a fee-schedule rate).
The top 5 billers nationally, ranked by 2024 Medicare service volume.
| # | Provider | Specialty | Location | Services | Est. Medicare paid |
|---|---|---|---|---|---|
| 1 | Luke Dreisbach, M.D. | Hematology-Oncology | Rancho Mirage, CA | 100,800 | $4.5M |
| 2 | Thomas Buroker, DO | Medical Oncology | Ankeny, IA | 89,600 | $3.9M |
| 3 | Mei Tang, MD | Hematology-Oncology | Baltimore, MD | 76,400 | $3.1M |
| 4 | John Waples, M.D. | Hematology-Oncology | Huntsville, AL | 73,600 | $3.3M |
| 5 | Steven Newman, MD | Internal Medicine | Naples, FL | 68,200 | $3.0M |
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